Baloxavir
Baloxavir marboxil is a first-in-class antiviral medication that targets influenza A and B viruses. It acts as a cap-dependent endonuclease inhibitor, which halts viral replication at an early stage. Unlike older antivirals that require multiple days of dosing, Baloxavir is administered as a convenient single-dose therapy.
Dosage by Body Weight
Administered as a single oral dose with or without food. To ensure proper absorption, avoid coadministration with dairy products, calcium-fortified beverages, or products containing polyvalent cations (such as laxatives, antacids, or multivitamins containing calcium, iron, magnesium, selenium, aluminum, or zinc).
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy have not been established in patients weighing less than 10 kg or infants under 1 year of age.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy have not been established in patients weighing less than 10 kg.
- Body Weight
- 8-10 kg
- Dose
- Not routinely recommended
- Frequency
- Use only if prescribed
- Tracking Notes
- Approval and standard weight-based guidelines start at 10 kg and above for pediatric patients aged 1 year and older.
- Body Weight
- 11-15 kg
- Dose
- 20 mg
- Frequency
- Single dose
- Tracking Notes
- The standard single dose for patients weighing 10 kg to less than 20 kg is 20 mg.
- Body Weight
- 16-20 kg
- Dose
- 20 mg
- Frequency
- Single dose
- Tracking Notes
- The standard single dose for patients weighing 10 kg to less than 20 kg is 20 mg.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Use only if prescribed | Safety and efficacy have not been established in patients weighing less than 10 kg or infants under 1 year of age. |
| 5-7 kg | Not recommended | Use only if prescribed | Safety and efficacy have not been established in patients weighing less than 10 kg. |
| 8-10 kg | Not routinely recommended | Use only if prescribed | Approval and standard weight-based guidelines start at 10 kg and above for pediatric patients aged 1 year and older. |
| 11-15 kg | 20 mg | Single dose | The standard single dose for patients weighing 10 kg to less than 20 kg is 20 mg. |
| 16-20 kg | 20 mg | Single dose | The standard single dose for patients weighing 10 kg to less than 20 kg is 20 mg. |
Formulation
Purpose
Treatment of acute uncomplicated influenza (flu) within 48 hours of symptom onset, and post-exposure prophylaxis (prevention) of influenza.
Generic Name
Baloxavir marboxilBranded Drug Names
Baloxavir is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.